Description

(S,S)-2,2'-Methylenebis(4-Phenyl-2-Oxazoline) is a high-purity chiral bis(oxazoline) ligand, a critical building block in asymmetric synthesis. Its value lies in its ability to act as a highly effective and enantioselective catalyst or ligand in a wide range of organic transformations, enabling the production of single-enantiomer compounds. This product is essential for research and development laboratories, pharmaceutical intermediates manufacturers, and fine chemical producers focused on creating optically active molecules with high stereochemical purity.

Application

• As a chiral ligand in asymmetric catalysis, including Diels-Alder, cyclopropanation, and aldol reactions.
• Key component in the synthesis of enantiomerically pure pharmaceutical intermediates and active pharmaceutical ingredients (APIs).
• Utilized in academic and industrial research for developing new asymmetric synthetic methodologies.
• Employed in the preparation of specialty polymers and advanced materials requiring chiral induction.
• Used in the synthesis of complex natural products and agrochemicals where stereocontrol is paramount.
• Acts as an organocatalyst or a metal complex ligand for enantioselective carbon-carbon and carbon-heteroatom bond formation.

Basic Information

Product Name	(S,S)-2,2'-Methylenebis(4-Phenyl-2-Oxazoline)
CAS No.	132098-59-0
Molecular Formula	C21H20N2O2
Molecular Weight	332.40 g/mol
Synonyms	(4S,4'S)-2,2'-Methylenebis(4-phenyl-4,5-dihydrooxazole); (S,S)-2,2'-(Methylenebis(4-phenyl-2-oxazoline); (S,S)-Methylenebis(4-phenyl-2-oxazoline); (S,S)-MBPO; (S,S)-Bis(4-phenyl-2-oxazolinyl)methane; Chiral bisoxazoline ligand; (S,S)-BOX ligand; (S,S)-2,2'-(Methylenebis(4,5-dihydro-4-phenyloxazole)
EINECS	Contact for details

Quality Control

Our (S,S)-2,2'-Methylenebis(4-Phenyl-2-Oxazoline) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high enantiomeric purity. Each lot is characterized using advanced analytical techniques, including chiral HPLC, to verify identity and purity. Certificates of Analysis (COA) detailing specific test results are provided with every shipment to support your quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at room temperature (15-25°C). Keep away from incompatible materials. This compound is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.