Description

5-[(1-Methylindole-3-Yl)Carbonyl]-4,5,6,7-Tetrahydro-1H-Bezimidazole is a high-purity, advanced pharmaceutical intermediate characterized by its unique fused heterocyclic structure. This compound is critical for research and development in medicinal chemistry, particularly in the synthesis of novel therapeutic agents targeting specific biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of complex, high-value active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and the development of new chemical entities (NCEs).
• Biochemical Reagent: Used in biochemical assays and as a reference standard for analytical method development and validation.
• Fine Chemical Synthesis: Intermediate for the production of more complex, functionalized benzimidazole and indole derivatives with specialized properties.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and process development services for the pharmaceutical industry.

Basic Information

Product Name	5-[(1-Methylindole-3-Yl)Carbonyl]-4,5,6,7-Tetrahydro-1H-Bezimidazole
CAS No.	132036-39-6
Molecular Formula	C18H17N3O
Molecular Weight	291.35 g/mol
Synonyms	1H-Benzimidazole-5-carboxylic acid, 4,5,6,7-tetrahydro-, 1-methyl-1H-indol-3-yl ester; 5-(1-Methyl-1H-indole-3-carbonyl)-4,5,6,7-tetrahydro-1H-benzimidazole; 5-[(1-Methyl-1H-indol-3-yl)carbonyl]-4,5,6,7-tetrahydro-1H-benzimidazole; 132036-39-6; 1-Methylindole-3-carboxylic acid 4,5,6,7-tetrahydro-1H-benzimidazol-5-yl ester
EINECS	Contact for details

Quality Control

Our 5-[(1-Methylindole-3-Yl)Carbonyl]-4,5,6,7-Tetrahydro-1H-Bezimidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical R&D. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your project specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.