Description

5-(Chloromethyl)-2-(Trifluoromethyl)Thiazole is a high-value, multi-functional heterocyclic building block characterized by its reactive chloromethyl and electron-withdrawing trifluoromethyl groups. This compound matters as a critical intermediate for synthesizing advanced agrochemicals and pharmaceuticals, enabling the introduction of key structural motifs that enhance bioactivity and metabolic stability. It is primarily needed by R&D chemists and process development teams in the agrochemical, pharmaceutical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Agrochemical Intermediate: Key precursor for the synthesis of novel herbicides, fungicides, and insecticides, leveraging the thiazole core for biological activity.
• Pharmaceutical Building Block: Used in medicinal chemistry to construct drug candidates, particularly in areas targeting infectious diseases and central nervous system disorders.
• Ligand and Catalyst Synthesis: Serves as a starting material for creating specialized ligands used in catalytic processes and material science.
• Functional Material Development: Incorporated into advanced polymers or organic electronic materials to modify electronic properties and stability.
• Custom Synthesis and Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for client-specific research and scale-up projects.

Basic Information

Product Name	5-(Chloromethyl)-2-(Trifluoromethyl)Thiazole
CAS No.	131748-98-6
Molecular Formula	C5H3ClF3NS
Molecular Weight	201.60 g/mol
Synonyms	2-(Trifluoromethyl)-5-(chloromethyl)thiazole; 5-(Chloromethyl)-2-(trifluoromethyl)-1,3-thiazole; 2-Trifluoromethyl-5-chloromethylthiazole; Thiazole, 5-(chloromethyl)-2-(trifluoromethyl)-; 131748-98-6; 5-Chloromethyl-2-trifluoromethylthiazole
EINECS	Contact for details

Quality Control

Every batch of 5-(Chloromethyl)-2-(Trifluoromethyl)Thiazole is produced and tested under a strict quality management system. We ensure compliance with relevant industry standards for fine chemical intermediates. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to verify identity, purity, and impurity profiles. A Certificate of Analysis (COA) detailing all test results is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after opening to prevent degradation from atmospheric moisture. Keep away from incompatible materials such as strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.