Description

(6-Trifluoromethyl-Pyridin-2-Yl)-Methanol is a high-value fluorinated pyridine derivative, a crucial building block in modern synthetic chemistry. Its importance lies in the trifluoromethyl group, which imparts unique electronic and metabolic properties to target molecules, enhancing their lipophilicity and bioavailability. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, serving as a key intermediate in the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A critical synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of drugs targeting the central nervous system, anti-infectives, and oncology therapeutics.
• Agrochemical Synthesis: Used in the production of advanced pesticides, herbicides, and fungicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand & Catalyst Development: Serves as a precursor for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the synthesis of fluorinated polymers and liquid crystals, contributing to materials with specific optical, electronic, or surface properties.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying enzyme mechanisms and biological pathways.

Basic Information

Product Name	(6-Trifluoromethyl-Pyridin-2-Yl)-Methanol
CAS No.	131747-53-0
Molecular Formula	C7H6F3NO
Molecular Weight	177.12 g/mol
Synonyms	2-(Hydroxymethyl)-6-(trifluoromethyl)pyridine; (6-(Trifluoromethyl)pyridin-2-yl)methanol; α-(Trifluoromethyl)-2-pyridinemethanol; 6-(Trifluoromethyl)-2-pyridinemethanol; 2-Pyridinemethanol, 6-(trifluoromethyl)-; (6-Trifluoromethyl-2-pyridyl)methanol
EINECS	Contact for details

Quality Control

We maintain stringent quality control protocols for our fluorinated intermediates. Each batch of (6-Trifluoromethyl-Pyridin-2-Yl)-Methanol is analyzed using advanced techniques including HPLC, GC, NMR, and MS to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment. Our quality system is designed to support cGMP and ISO standards for traceability and reliability in regulated applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.