Description

n-(3-Butenyl) Noroxymorphone Hydrochloride is a high-purity pharmaceutical intermediate and research chemical, specifically a synthetic derivative of the opioid antagonist noroxymorphone. This compound is of significant value for its role in advanced medicinal chemistry research and the development of novel therapeutic agents targeting opioid receptors. It is primarily utilized by pharmaceutical R&D laboratories, academic research institutions, and fine chemical manufacturers engaged in the synthesis of specialized active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel opioid receptor modulators and analgesic compounds.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to develop new therapeutic agents with targeted pharmacological profiles.
• Reference Standard: Serves as a certified reference material (CRM) for analytical method development and quality control in pharmaceutical analysis.
• Biochemical Research: Employed in in vitro studies to investigate opioid receptor binding, signaling pathways, and antagonist effects.
• Process Development: Utilized in scaling up synthetic routes for the production of specialized active pharmaceutical ingredients (APIs).

Basic Information

Product Name	n-(3-Butenyl) Noroxymorphone Hydrochloride
CAS No.	131670-05-8
Molecular Formula	C₂₂H₂₈ClNO₄
Molecular Weight	405.92 g/mol
Synonyms	17-(3-Buten-1-yl)-4,5α-epoxy-3,14-dihydroxymorphinan-6-one hydrochloride; Noroxymorphone N-(3-butenyl) hydrochloride; 4,5α-Epoxy-3,14-dihydroxy-17-(3-butenyl)morphinan-6-one hydrochloride; 6-Oxo-noroxymorphone 3-butenyl derivative HCl; NBN Hydrochloride
EINECS	Contact for details

Quality Control

Our n-(3-Butenyl) Noroxymorphone Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation via IR and NMR spectroscopy, and residual solvent analysis, to ensure it meets exacting standards for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming batch-specific results and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption. For long-term storage, consider desiccants or an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.