Description

1,7,8-Indolizinetriol, 6-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is a complex, stereochemically defined fluorinated indolizine derivative, serving as a high-value synthetic intermediate for advanced pharmaceutical research and development. Its precise stereochemistry and functional group array make it a critical building block for constructing novel bioactive molecules, particularly in medicinal chemistry programs targeting complex diseases. This compound is primarily sought by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of potential drug candidates and other specialized organic materials.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and synthesis of novel active pharmaceutical ingredients (APIs), especially in neurological and metabolic disorder research.
• Medicinal Chemistry Research: Used as a core scaffold or advanced building block in structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry Development: Serves as a critical starting material or intermediate in the development and scale-up of synthetic routes for complex molecules.
• Agrochemical Research: Potential intermediate in the discovery and development of new generation pesticides or herbicides with specific modes of action.
• Academic & Institutional Research: Utilized in universities and research institutes for methodological studies in organic synthesis, fluorination chemistry, and asymmetric synthesis.
• Fine Chemical Synthesis: Employed in the custom synthesis of specialty chemicals, ligands, or catalysts requiring a specific, multi-functionalized indolizine structure.

Basic Information

Product Name	1,7,8-Indolizinetriol, 6-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)-
CAS No.	131635-62-6
Molecular Formula	C8H14FNO3
Molecular Weight	191.20 g/mol
Synonyms	(1S,6S,7R,8R,8aR)-6-Fluorooctahydro-1,7,8-indolizinetriol; 6-Fluoro-1,7,8-trihydroxyoctahydroindolizine (1S,6S,7R,8R,8aR)-; (1S,6S,7R,8R,8aR)-6-Fluoro-1,2,3,5,6,7,8,8a-octahydroindolizine-1,7,8-triol; 6-Fluorooctahydro-1,7,8-indolizinetriol (1S,6S,7R,8R,8aR)-; Fluorinated Indolizinetriol Derivative; 131635-62-6 (CAS Name); 1S-(1α,6β,7α,8β,8aβ)-6-Fluorooctahydro-1,7,8-indolizinetriol
EINECS	Contact for details

Quality Control

Every batch of 1,7,8-Indolizinetriol, 6-Fluorooctahydro-, 1S-(1.Alpha.,6.Beta.,7.Alpha.,8.Beta.,8A.Beta.)- is manufactured and analyzed under strict quality management systems. Our products undergo rigorous identity, purity, and chiral purity testing using advanced analytical techniques such as HPLC, GC, NMR, and chiral chromatography to ensure compliance with exacting R&D and process chemistry standards. A comprehensive Certificate of Analysis (COA) detailing batch-specific results is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Chiral Purity (Chiral HPLC)	≥ 98.0% ee
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.