Description

1H-Indazole, 3-(4-Methyl-1-Piperazinyl)- is a high-purity, heterocyclic organic compound featuring a fused indazole core substituted with a methylpiperazine moiety. This specific molecular architecture makes it a critical intermediate and building block in advanced organic synthesis, particularly for pharmaceutical research and development. It is primarily sought after by R&D chemists and process development scientists in the life sciences sector for creating novel active pharmaceutical ingredients (APIs) and other biologically active molecules.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and production of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Chemical Synthesis Building Block: Used in the construction of complex heterocyclic compounds for medicinal chemistry and agrochemical research.
• Biochemical Research: Employed as a reference standard or ligand in biochemical assays and pharmacological studies to investigate receptor interactions.
• Academic & Institutional R&D: Serves as a starting material for novel methodological studies in organic chemistry and drug discovery programs.

Basic Information

Product Name	1H-Indazole, 3-(4-Methyl-1-Piperazinyl)-
CAS No.	131634-01-0
Molecular Formula	C12H16N4
Molecular Weight	216.28 g/mol
Synonyms	3-(4-Methylpiperazin-1-yl)-1H-indazole; 3-(4-Methyl-1-piperazinyl)-1H-indazole; 1H-Indazole-3-yl-4-methylpiperazine; 4-Methyl-1-(1H-indazol-3-yl)piperazine; 3-(N-Methylpiperazino)indazole; L-741,626 (a known dopamine D2/D3 receptor antagonist); L741626; L 741626
EINECS	Contact for details

Quality Control

Our production of 1H-Indazole, 3-(4-Methyl-1-Piperazinyl)- adheres to stringent internal quality protocols to ensure batch-to-batch consistency and high purity. Each lot is characterized and tested using advanced analytical techniques including HPLC, GC, NMR, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.