Description

Arecoline-D5, Hydrobromide Salt is a deuterated internal standard of the alkaloid arecoline, specifically labeled with five deuterium atoms and supplied as its hydrobromide salt. This high-purity compound is essential for ensuring accuracy and reliability in quantitative analytical methods, particularly mass spectrometry. It is a critical tool for researchers and quality control laboratories in the pharmaceutical, forensic, and toxicology sectors requiring precise measurement of arecoline and its metabolites.

Application

• Primary use as a deuterated internal standard for the quantification of arecoline in complex biological matrices via LC-MS/MS and GC-MS.
• Method development and validation in pharmacokinetic and metabolic studies related to betel nut alkaloids.
• Quality control and assurance in the manufacturing of pharmaceutical reference materials and diagnostic kits.
• Forensic analysis and clinical toxicology for the accurate detection and measurement of arecoline exposure.
• Supporting research in neuroscience and addiction studies investigating the cholinergic effects of arecoline.
• Calibration standard for ensuring regulatory compliance in analytical testing laboratories.

Basic Information

Product Name	Arecoline-D5, Hydrobromide Salt
CAS No.	131448-18-5
Molecular Formula	C8H8D5NO2·HBr
Molecular Weight	Contact for details
Synonyms	Arecoline-d5 HBr; 1,2,5,6-Tetrahydro-1-methyl-3-pyridinecarboxylic acid methyl ester-d5 hydrobromide; Methyl 1-methyl-1,2,5,6-tetrahydropyridine-3-carboxylate-d5 hydrobromide; Arecoline (methyl-d3, 3,4,5-d2) hydrobromide; Deuterated Arecoline Hydrobromide; Arecoline Internal Standard; [2H5]-Arecoline Hydrobromide
EINECS	Contact for details

Quality Control

Every batch of Arecoline-D5, Hydrobromide Salt is manufactured and analyzed under strict quality management protocols. We guarantee high chemical and isotopic purity, verified by advanced spectroscopic and chromatographic techniques. A comprehensive Certificate of Analysis (COA) detailing purity (by HPLC/NMR), isotopic enrichment, and identity confirmation is provided with each shipment to ensure it meets the exacting standards for analytical research and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a desiccated environment to maintain stability and purity. Handle under an inert atmosphere if prolonged exposure is anticipated during use.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Isotopic Purity	≥ 98 atom % D
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.