Description

1-Trichloromethyl-1,2,3,4-Tetrahydro-β-Carboline is a specialized heterocyclic organic compound that serves as a valuable synthetic intermediate and building block in advanced chemical research. Its unique molecular framework, incorporating a tetrahydro-β-carboline core with a reactive trichloromethyl group, makes it a versatile precursor for the development of novel pharmacologically active compounds. This high-purity chemical is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries focused on creating new active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) targets, due to the privileged β-carboline scaffold.
• Agrochemical Research: Used in the development of new pesticides and herbicides, where the trichloromethyl moiety can impart specific biological activity.
• Organic Synthesis Reagent: Serves as a versatile precursor for constructing complex heterocyclic systems and introducing functional groups in medicinal chemistry.
• Biochemical Research: Employed in studies investigating enzyme inhibition and receptor-ligand interactions, given the structural similarity to natural alkaloids.
• Material Science Precursor: Potential use in the synthesis of specialized organic materials and ligands for catalytic systems.

Basic Information

Product Name	1-Trichloromethyl-1,2,3,4-Tetrahydro-β-Carboline
CAS No.	131384-80-0
Molecular Formula	C₁₃H₁₁Cl₃N₂
Molecular Weight	293.60 g/mol
Synonyms	1-(Trichloromethyl)-1,2,3,4-tetrahydro-9H-pyrido[3,4-b]indole; 1-(Trichloromethyl)-1,2,3,4-tetrahydro-β-carboline; 9H-Pyrido[3,4-b]indole, 1,2,3,4-tetrahydro-1-(trichloromethyl)-; TCM-THC; 1-Trichloromethyl-THBC; 1-TCM-1,2,3,4-THBC; 1-(Trichloromethyl)-1,2,3,4-tetrahydro-β-carboline
EINECS	Contact for details

Quality Control

Our 1-Trichloromethyl-1,2,3,4-Tetrahydro-β-Carboline is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity. We provide comprehensive analytical data, including HPLC purity, identity confirmation (IR, NMR), and impurity profiling. A Certificate of Analysis (COA) is supplied with each batch, detailing all relevant specifications. Our quality system is designed to meet the rigorous standards required for research and development applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.