Description

Cyclopenta[B]Pyrrol-2(1H)-One, Hexahydro-, (3Ar-Cis)- (9Ci) is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry. This compound is of significant value for its role as a key building block in the synthesis of complex, biologically active molecules. It is primarily needed by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly within medicinal chemistry and process R&D.

Application

• Pharmaceutical Intermediate: Serves as a critical chiral synthon in the multi-step synthesis of novel active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used as a scaffold or precursor for constructing compound libraries in drug discovery programs targeting various disease pathways.
• Process Chemistry Development: Employed in route scouting and optimization for the scalable production of candidate drugs.
• Asymmetric Synthesis: Utilized in stereoselective reactions to introduce complex molecular architectures due to its defined cis-configuration.
• Fine Chemical Synthesis: Acts as a starting material or intermediate for the preparation of other specialized fine chemicals and agrochemicals.

Basic Information

Product Name	Cyclopenta[B]Pyrrol-2(1H)-One, Hexahydro-, (3Ar-Cis)- (9Ci)
CAS No.	131348-75-9
Molecular Formula	C7H11NO
Molecular Weight	125.17 g/mol
Synonyms	(3aR,7aS)-Hexahydro-1H-cyclopenta[b]pyrrol-2(3H)-one; (3aR-cis)-Octahydro-2H-cyclopenta[b]pyrrol-2-one; cis-Hexahydrocyclopenta[b]pyrrol-2(1H)-one; (3aR,7aS)-Octahydro-2H-cyclopenta[b]pyrrol-2-one; 2(1H)-Cyclopenta[b]pyrrolone, hexahydro-, (3aR-cis)-; A key chiral lactam intermediate.
EINECS	Contact for details

Quality Control

Our Cyclopenta[B]Pyrrol-2(1H)-One, Hexahydro-, (3Ar-Cis)- (9Ci) is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, and impurity profiles.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (typically 15-25°C). Keep away from incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.