Description

2-Pyrimidinethiol (9Ci) is a sulfur-containing heterocyclic compound that serves as a versatile and critical building block in advanced organic synthesis. Its value lies in its role as a key precursor for the development of pharmaceuticals, agrochemicals, and functional materials. This high-purity intermediate is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to develop novel active ingredients and ligands.

Application

• Pharmaceutical Intermediate: A crucial building block for the synthesis of active pharmaceutical ingredients (APIs), particularly in antiviral, anticancer, and central nervous system (CNS) drug candidates.
• Agrochemical Synthesis: Used in the development of novel herbicides, fungicides, and insecticides, where the pyrimidine core provides key biological activity.
• Ligand and Catalyst Preparation: Serves as a precursor for creating specialized ligands used in transition metal catalysis and coordination chemistry.
• Material Science Research: Employed in the synthesis of organic electronic materials, such as components for OLEDs or conductive polymers.
• Chemical Biology & Proteomics: Utilized as a reactive handle or tagging agent in bioconjugation and probe development.
• Custom Synthesis & Contract Manufacturing: A starting material for bespoke chemical synthesis services catering to R&D and pilot-scale production.

Basic Information

Product Name	2-Pyrimidinethiol (9Ci)
CAS No.	131242-36-9
Molecular Formula	C4H4N2S
Molecular Weight	112.15 g/mol
Synonyms	2-Mercaptopyrimidine; Pyrimidine-2-thiol; 2-Pyrimidinethiol; 2-Thiopyrimidone; 2(1H)-Pyrimidinethione; 2-Pyrimidinol, thio-; 1H-Pyrimidine-2-thione; 2-Sulfanylpyrimidine
EINECS	Contact for details

Quality Control

Every batch of 2-Pyrimidinethiol is produced and tested under a strict quality management system. We provide material that meets high-purity standards suitable for research and industrial synthesis. Comprehensive analytical testing, including HPLC, GC, and NMR, is performed to ensure identity, purity, and consistency. A Certificate of Analysis (COA) detailing all specifications is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended storage temperature is 2-8°C for long-term stability. This compound is easily oxidized (store under inert atmosphere). Keep away from strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.