Description

Thiophene, 3,4-Dichlorotetrahydro-, trans- (9Ci) is a halogenated, saturated thiophene derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and valuable chiral building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique stereochemistry and functional groups make it essential for researchers and process chemists engaged in the synthesis of active pharmaceutical ingredients (APIs), specialty chemicals, and novel materials. The CAS number for this product is 131211-73-9.

Application

This specialized intermediate is utilized in a variety of high-value synthetic pathways.

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and enzyme inhibitors.
• Agrochemical Synthesis: Used in the creation of advanced pesticides and herbicides, where the dichloro and tetrahydrothiophene motifs can contribute to biological activity.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing specialized ligands used in asymmetric catalysis and transition metal complexes.
• Material Science Research: Investigated as a monomer or building block for novel polymers and functional materials with specific electronic or structural properties.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic compounds and natural product analogs.

Basic Information

Item	Detail
Product Name	Thiophene, 3,4-Dichlorotetrahydro-, trans- (9Ci)
CAS No.	131211-73-9
Molecular Formula	C4H6Cl2S
Molecular Weight	157.06 g/mol
Synonyms	trans-3,4-Dichlorotetrahydrothiophene; (3R,4R)-3,4-Dichlorotetrahydrothiophene; (3S,4S)-3,4-Dichlorotetrahydrothiophene; Tetrahydro-3,4-dichlorothiophene; 3,4-Dichlorotetrahydrothiophene; 131211-73-9; trans-3,4-Dichlorothiolane
EINECS	Contact for details

Quality Control

Our production of Thiophene, 3,4-Dichlorotetrahydro-, trans- (9Ci) adheres to stringent quality protocols to ensure batch-to-batch consistency and high purity for research and scale-up applications. Each lot is supported by a comprehensive Certificate of Analysis (COA) detailing purity, enantiomeric excess (where applicable), and impurity profiles. We employ advanced analytical techniques including GC, HPLC, and NMR to verify identity and quality, ensuring the material meets the exacting standards required for synthetic chemistry.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at room temperature (15-25°C). This compound is compatible with strong acids and organic solvents but should be kept away from incompatible materials. Keep container tightly sealed when not in use to prevent moisture absorption or contamination.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 97.0%
trans-Isomer Content	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.