Description

Benzenethiol, 6-Amino-2-Fluoro-3-Methyl- (9Ci) is a specialized aromatic thiol derivative featuring amino and fluoro substituents, making it a valuable multi-functional building block for advanced synthesis. Its unique structure provides a reactive thiol group alongside an aromatic amine, enabling its use in the creation of complex heterocycles and functional materials. This compound is primarily sought by research and development chemists in the pharmaceutical and agrochemical sectors for the synthesis of novel active ingredients and intermediates.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and oncology.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the fluorine atom enhances biological activity and metabolic stability.
• Ligand and Catalyst Development: Serves as a building block for creating specialized ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the synthesis of functional polymers and organic electronic materials due to its conjugated aromatic system and reactive sites.
• Chemical Biology Probes: Utilized to develop fluorescent probes and activity-based protein profiling (ABPP) agents that exploit the reactivity of the thiol group.
• Cross-coupling Reactions: Acts as a substrate in palladium-catalyzed cross-coupling reactions, such as Buchwald-Hartwig amination, to form complex biaryl structures.

Basic Information

Product Name	Benzenethiol, 6-Amino-2-Fluoro-3-Methyl- (9Ci)
CAS No.	131105-94-7
Molecular Formula	C7H8FNS
Molecular Weight	157.21 g/mol
Synonyms	2-Fluoro-3-methyl-6-aminobenzenethiol; 6-Amino-2-fluoro-3-methylbenzenethiol; 2-Amino-5-fluoro-6-mercaptotoluene; 2-Fluoro-6-mercapto-3-methylaniline; 3-Methyl-2-fluoro-6-aminothiophenol; 2-Fluoro-3-methyl-6-aminophenyl mercaptan; 6-Amino-2-fluoro-3-methylthiophenol
EINECS	Contact for details

Quality Control

Every batch of Benzenethiol, 6-Amino-2-Fluoro-3-Methyl- (9Ci) is produced and tested under a strict quality management system. We employ advanced analytical techniques including HPLC, GC, and NMR to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all test results is provided with each shipment to guarantee it meets your specific research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) at a controlled room temperature (15-25°C) in a cool, dry, and well-ventilated area. Due to its sensitivity to oxidation and light, prolonged exposure to air or light should be avoided to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.