Description

Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-(Acetylamino)-, (1R-Exo)- (9Ci) CAS NO 131102-02-8 is a high-purity, stereochemically defined chiral building block derived from norbornene. This compound matters for its role as a key synthetic intermediate in the development of advanced pharmaceuticals and fine chemicals, where its rigid bicyclic framework and specific stereochemistry are critical for imparting desired biological activity and material properties. It is primarily needed by research and development chemists, process development teams, and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors.

Application

• Pharmaceutical Intermediate: Serves as a crucial chiral synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for central nervous system (CNS) and antiviral drug candidates.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides and herbicides, where its structural complexity can contribute to selective biological activity.
• Ligand and Catalyst Development: Acts as a precursor for creating specialized chiral ligands and organocatalysts used in asymmetric synthesis.
• Polymer Science: Employed in the synthesis of specialty polymers and resins, leveraging the norbornene moiety for ring-opening metathesis polymerization (ROMP) or other polymerization techniques to create materials with unique thermal and mechanical properties.
• Academic and Industrial R&D: A valuable tool for methodological development in organic chemistry, enabling studies in stereoselective synthesis and molecular design.
• Fine Chemical Production: Utilized in the multi-step synthesis of complex, high-value fine chemicals and flavors & fragrances.

Basic Information

Product Name	Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-(Acetylamino)-, (1R-Exo)- (9Ci)
CAS No.	131102-02-8
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	(1R-exo)-2-(Acetylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; 2-Acetamido-5-norbornene-2-carboxylic acid, (1R-endo,2S-exo)-; N-Acetyl-5-norbornene-2-carboxamide-2-carboxylic acid; exo-2-Acetamidobicyclo[2.2.1]hept-5-ene-2-carboxylic acid; (1R,2S,4R)-2-(Acetylamino)bicyclo[2.2.1]hept-5-ene-2-carboxylic acid; Bicyclo[2.2.1]hept-5-ene-2-carboxylic acid, 2-(acetylamino)-, (1R,2S,4R)-; Norbornene derivative chiral building block.
EINECS	Contact for details

Quality Control

Our Bicyclo[2.2.1]Hept-5-Ene-2-Carboxylic Acid, 2-(Acetylamino)-, (1R-Exo)- (9Ci) is produced under strict quality management systems. Every batch undergoes rigorous analytical testing, including chiral purity verification by HPLC, to ensure high chemical and stereochemical purity suitable for demanding synthetic applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This compound may be hygroscopic; keep the container tightly sealed to minimize exposure to moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.