Description

(S)-4,5-Isopropylidene-1-Bromopentane CAS NO 130995-39-0 is a high-purity chiral building block, a brominated intermediate featuring a protected diol functionality. This compound is valued for its role in the stereoselective synthesis of complex molecules, enabling the construction of specific chiral centers with high fidelity. It is primarily required by research institutions and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs), nucleoside analogs, and other specialty chemicals.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the synthesis of antiviral and anticancer drug candidates.
• Nucleoside Chemistry: Used in the preparation of modified nucleosides and nucleotides for medicinal chemistry and biochemical research.
• Asymmetric Synthesis: Serves as a versatile electrophile in C-C bond-forming reactions, such as alkylations, to introduce chiral pentyl chains.
• Natural Product Synthesis: Employed in the total synthesis of complex natural products requiring specific stereochemistry.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands used in asymmetric catalysis.
• Polymer Science: Potential monomer or initiator for creating polymers with tailored chiral properties.

Basic Information

Product Name	(S)-4,5-Isopropylidene-1-Bromopentane
CAS No.	130995-39-0
Molecular Formula	C8H15BrO2
Molecular Weight	223.11 g/mol
Synonyms	(S)-1-Bromo-4,5-O-isopropylidene-1-pentanol; (S)-1-Bromo-4,5-O-isopropylidenepentane; (S)-1-Bromo-4,5-O-isopropylidenepentanol; (S)-4,5-O-Isopropylidene-1-bromopentane; (S)-1-Bromo-4,5-O-(1-methylethylidene)pentane; (S)-1-Bromo-4,5-O-(1-methylethylidene)pentanol; (S)-1-Bromo-4,5-O-(1-methylethylidene)-1-pentanol; (S)-1-Bromo-4,5-O-(1-methylethylidene)pentane-1-ol
EINECS	Contact for details

Quality Control

Our (S)-4,5-Isopropylidene-1-Bromopentane is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure compliance with exacting standards for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and enantiomeric excess is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at 2-8°C or as specified on the label. Keep away from strong acids and incompatible organic solvents. For long-term storage under inert atmosphere, please inquire.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.