Description

Dodecylphosphorylcholine-D38 is a deuterated isotopologue of dodecylphosphorylcholine, a synthetic phospholipid analog. This compound is specifically valued for its role as a stable isotope-labeled internal standard in quantitative mass spectrometry, ensuring unparalleled accuracy in analytical measurements. It is an essential tool for researchers and quality control laboratories in the pharmaceutical, biotechnology, and advanced materials sectors who require precise quantification of phospholipids and related surfactants.

Application

• Quantitative Mass Spectrometry (MS): Serves as a critical deuterated internal standard for the accurate quantification of natural dodecylphosphorylcholine and related lipid species in LC-MS and GC-MS workflows.
• Pharmaceutical R&D: Used in pharmacokinetic and metabolomic studies to track the absorption, distribution, metabolism, and excretion (ADME) of phospholipid-based drug candidates and excipients.
• Biomembrane Research: Employed in studies of membrane dynamics, lipid-protein interactions, and the assembly of synthetic membranes due to its defined chemical structure.
• Analytical Method Development: Essential for validating and calibrating analytical methods in compliance with regulatory guidelines (e.g., FDA, ICH Q2) for impurity profiling and assay determination.
• Surfactant & Detergent Studies: Acts as a model compound for investigating the physicochemical properties and biological effects of alkylphosphorylcholine surfactants.

Basic Information

Item	Details
Product Name	Dodecylphosphorylcholine-D38
CAS No.	130890-78-7
Molecular Formula	C₁₇D₃₈NO₄P
Molecular Weight	~384.6 (deuterated form)
Synonyms	1-Dodecanoyl-2-hydroxy-sn-glycero-3-phosphocholine-D38; LPC(12:0)-D38; LysoPC(12:0)-D38; 1-Lauroyl-2-hydroxy-sn-glycero-3-phosphocholine-D38; Deuterated Dodecylphosphorylcholine; D38-LysoPC; Deuterium Labeled Lysophosphatidylcholine C12:0; DPC-D38
EINECS	Contact for details

Quality Control

Every batch of Dodecylphosphorylcholine-D38 is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including NMR and mass spectrometry to confirm deuteration level and identity. A Certificate of Analysis (COA) detailing purity, isotopic enrichment, and analytical results is provided with each shipment to ensure traceability and compliance with your research or quality protocols.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below. This product is hygroscopic (moisture-sensitive). Allow the sealed vial to equilibrate to room temperature before opening to minimize moisture condensation. For long-term storage, keep desiccated.

Specification

Item	Specification
Appearance	White to off-white solid or film
Identification (NMR/MS)	Conforms to structure
Purity (HPLC)	≥ 95%
Isotopic Enrichment	≥ 98 atom % D
Chemical Purity (Titration)	≥ 90%
Water Content (KF)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.