Description

Cyclohexanone, 4-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]- is a high-value, protected intermediate featuring a tert-butyldiphenylsilyl (TBDPS) ether group. This compound is specifically engineered to provide superior stability and controlled reactivity in complex synthetic pathways, particularly where sensitive functional groups are present. It is a critical building block for researchers and manufacturers in the pharmaceutical and advanced organic synthesis sectors, enabling the production of novel active pharmaceutical ingredients (APIs) and fine chemicals.

Application

• Pharmaceutical Intermediate: A key protected synthon in the multi-step synthesis of complex drug molecules and active pharmaceutical ingredients (APIs).
• Advanced Organic Synthesis: Used as a building block for constructing complex natural products, agrochemicals, and specialty materials.
• Peptide and Carbohydrate Chemistry: Serves as a protecting group for hydroxyl functions during the synthesis of sensitive biomolecules.
• Asymmetric Synthesis: Employed in chiral synthesis where the steric bulk of the TBDPS group provides crucial stereochemical control.
• Material Science Research: A precursor in the development of novel organic frameworks and functionalized polymers.
• Process Chemistry Development: Used in route scouting and optimization for scalable manufacturing processes in fine chemical production.

Basic Information

Item	Detail
Product Name	Cyclohexanone, 4-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]-
CAS No.	130745-59-4
Molecular Formula	C22H28O2Si
Molecular Weight	352.55 g/mol
Synonyms	4-[(tert-Butyldiphenylsilyl)oxy]cyclohexanone; 4-(TBDPS-oxy)cyclohexanone; 4-(tert-Butyldiphenylsilyloxy)cyclohexanone; 4-TBDPSO-Cyclohexanone; 4-[(1,1-Dimethylethyl)diphenylsilyl]oxy]cyclohexanone; 4-(tert-Butyldiphenylsiloxy)cyclohexanone; Cyclohexanone, 4-[(tert-butyldiphenylsilyl)oxy]-
EINECS	Contact for details

Quality Control

Our Cyclohexanone, 4-[[(1,1-Dimethylethyl)Diphenylsilyl]Oxy]- is produced under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistent performance. We provide comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles. Our quality commitment aligns with the standards required for GMP-influenced starting materials and advanced research applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); ensure containers are sealed tightly after use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.