Description

2-Amino-3-Methyl-Butanoic-3,4-T2 Acid (9Ci) is a specialized amino acid derivative of significant interest in advanced chemical synthesis and research. This compound serves as a crucial chiral building block and a potential precursor for the development of novel pharmaceuticals and biochemical probes. It is primarily sought after by research institutions and industrial R&D departments focused on medicinal chemistry, peptide synthesis, and isotopic labeling studies. The product is supplied with a high level of purity and batch-to-batch consistency to meet stringent research and development requirements.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs), particularly for metabolic and neurological targets.
• Peptide Chemistry: Used as a modified amino acid residue in the synthesis of specialized peptides and peptidomimetics for biochemical research.
• Isotopic Labeling Studies: The tritium (T2) label makes it valuable as a tracer molecule in metabolic pathway analysis, receptor binding assays, and pharmacokinetic studies.
• Biochemical Research: Employed in the study of enzyme mechanisms and amino acid metabolism due to its structural specificity.
• Reference Standard: Serves as an analytical standard for quality control and method development in laboratories analyzing complex biological matrices.
• Agrochemical Research: Potential application as an intermediate in the development of novel, targeted plant growth regulators or herbicides.

Basic Information

Product Name	2-Amino-3-Methyl-Butanoic-3,4-T2 Acid (9Ci)
CAS No.	130421-56-6
Molecular Formula	C5H9T2NO2
Molecular Weight	~119.14 g/mol (unlabeled base: 117.15)
Synonyms	L-Valine-3,4-T2; 3,4-Ditritio-L-valine; (2S)-2-Amino-3-methyl-3,4-ditritiobutanoic acid; 2-Amino-3-methylbutanoic-3,4-T2 acid; L-Valine (3,4-T2); 3-Methyl-2-aminobutanoic-3,4-T2 acid; T2-labeled L-Valine; Amino acid V (T2)
EINECS	Contact for details

Quality Control

Every batch of 2-Amino-3-Methyl-Butanoic-3,4-T2 Acid (9Ci) is produced and analyzed under strict quality management protocols. We ensure high chemical and isomeric purity, along with specific radiochemical purity and activity for the tritium label. Our quality assurance includes comprehensive analytical techniques such as HPLC, NMR, and mass spectrometry. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting identity, purity, specific activity, and solvent content.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) or as specified on the label. This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability. For long-term storage of solutions, consider conditions recommended for radiolabeled compounds.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95% (Chemical)
Radiochemical Purity	≥ 97%
Specific Activity	Contact for details
Optical Rotation	[α]²⁰D: +X to +Y (c=1 in H₂O)
Solvent Content (Residual)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.