Description

1-(2-Bromoethyl)-4-(Trifluoromethyl)Benzene, also known as 2-(4-Trifluoromethylphenyl)Ethyl Bromide, is a versatile and high-value organic building block. This compound is critical for introducing the 2-(4-trifluoromethylphenyl)ethyl moiety into more complex molecular architectures, a key step in the development of advanced materials and active pharmaceutical ingredients. It is primarily sought after by research chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for constructing novel compounds with tailored properties.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders, inflammation, and metabolic diseases where the trifluoromethyl group enhances metabolic stability and lipophilicity.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides, leveraging the bioactivity-modifying properties of the bromoethyl and trifluoromethylphenyl groups.
• Liquid Crystal & OLED Material Precursor: Serves as a building block for creating advanced organic electronic materials, including charge-transport layers and emissive compounds for displays and lighting.
• Ligand & Catalyst Development: Employed in the preparation of specialized phosphine or nitrogen-based ligands for transition metal catalysis, enabling more efficient and selective chemical transformations.
• Polymer & Resin Modifier: Incorporated into polymer chains to impart specific characteristics such as altered refractive index, enhanced chemical resistance, or unique surface properties.
• Cross-Coupling Reactions: Acts as an efficient electrophile in palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Negishi) for carbon-carbon bond formation in complex molecule assembly.

Basic Information

Product Name	1-(2-Bromoethyl)-4-(Trifluoromethyl)Benzene
CAS No.	130365-87-6
Molecular Formula	C9H8BrF3
Molecular Weight	253.06 g/mol
Synonyms	2-(4-Trifluoromethylphenyl)Ethyl Bromide; 4-(2-Bromoethyl)benzotrifluoride; 1-Bromo-2-[4-(trifluoromethyl)phenyl]ethane; (4-Trifluoromethylphenethyl) Bromide; α-Bromo-4-(trifluoromethyl)toluene; 2-Bromo-1-[4-(trifluoromethyl)phenyl]ethane; 4-(2-Bromoethyl)α,α,α-trifluorotoluene; β-Bromo-4-(trifluoromethyl)phenethyl bromide
EINECS	Contact for details

Quality Control

Our 1-(2-Bromoethyl)-4-(Trifluoromethyl)Benzene is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity, identity, and consistency, meeting the stringent requirements for research and process chemistry. Comprehensive Certificates of Analysis (COA) detailing purity, assay, and impurity profiles are provided with every shipment to support your quality and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from strong bases and incompatible materials. The container should be kept tightly sealed to prevent moisture ingress and decomposition.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.