Description

1,16-Hexadecanedioic-D28 Acid is a high-purity, deuterium-labeled analog of hexadecanedioic acid, a long-chain dicarboxylic acid. This stable isotope-labeled compound is essential for advanced analytical research, providing a critical internal standard for precise quantification and metabolic pathway tracing. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and analytical chemistry sectors for applications in mass spectrometry, NMR spectroscopy, and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analyses for accurate measurement of hexadecanedioic acid and related metabolites in complex biological matrices.
• Metabolic Pathway Tracing: Enables the study of fatty acid metabolism, β-oxidation cycles, and dicarboxylic acid pathways in pharmacokinetic and biomedical research.
• NMR Spectroscopy: Serves as a deuterated probe in nuclear magnetic resonance studies to elucidate molecular structure and dynamics without signal interference from protons.
• Pharmaceutical Impurity Profiling: Aids in the identification and quantification of process-related impurities and degradants in drug substance development.
• Biomarker Research: Facilitates the discovery and validation of disease biomarkers related to metabolic disorders by providing a stable isotope-labeled comparator.
• Chemical Synthesis Intermediate: Acts as a labeled building block for the synthesis of more complex deuterated compounds, polymers, or specialty materials.

Basic Information

Product Name	1,16-Hexadecanedioic-D28 Acid
CAS No.	130348-90-2
Molecular Formula	C₁₆D₂₈O₄
Molecular Weight	316.55 g/mol
Synonyms	Hexadecanedioic-D28 Acid; Deuterated Hexadecanedioic Acid; D28-Hexadecanedioic Acid; 1,16-Dideuterohexadecanedioic Acid (fully deuterated); Thapsic-D28 Acid; Hexadecane-1,16-dioic-D28 Acid; [D28]-1,16-Hexadecanedioic Acid; Perdeuterohexadecanedioic Acid
EINECS	Contact for details

Quality Control

Our 1,16-Hexadecanedioic-D28 Acid is produced under strict quality management systems to ensure exceptional isotopic purity and chemical integrity. Each batch is characterized by advanced analytical techniques including NMR, MS, and HPLC to confirm deuterium incorporation and chemical purity. A comprehensive Certificate of Analysis (COA) detailing isotopic enrichment, assay, and impurity profile is provided with every shipment to support your research and compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is sealed after each use to minimize exposure to atmospheric humidity. For long-term storage, consider using desiccants or storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Deuterium Enrichment (NMR/MS)	≥ 98 atom % D
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.