Description

(S)-(-)-1,1,1-Trifluoroheptan-2-Ol CAS NO 130025-35-3 is a high-purity chiral fluorinated alcohol, serving as a critical chiral building block and intermediate in advanced organic synthesis. Its value lies in the unique combination of a stereogenic center and the trifluoromethyl group, which can significantly influence the biological activity and physicochemical properties of target molecules. This compound is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries developing novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in medicinal chemistry programs targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, where the fluorine atoms enhance lipophilicity, metabolic stability, and membrane permeability.
• Liquid Crystal & Advanced Material Precursor: Serves as a building block for fluorinated liquid crystals and specialty polymers that require specific optical and electronic properties.
• Asymmetric Catalysis & Ligand Synthesis: Employed in the preparation of chiral ligands and catalysts for enantioselective transformations in fine chemical manufacturing.
• Analytical Standard & Reference Material: Provided as a high-purity standard for quality control, method development, and regulatory submissions in analytical laboratories.

Basic Information

Product Name	(S)-(-)-1,1,1-Trifluoroheptan-2-Ol
CAS No.	130025-35-3
Molecular Formula	C7H11F3O
Molecular Weight	168.16 g/mol
Synonyms	(S)-1,1,1-Trifluoroheptan-2-ol; (S)-(-)-1,1,1-Trifluoro-2-heptanol; (2S)-1,1,1-Trifluoroheptan-2-ol; (S)-2-Heptanol, 1,1,1-trifluoro-; (S)-α-Trifluoromethylheptyl alcohol; (S)-HepTFOH; (S)-HepTFOL; (S)-1,1,1-Trifluoro-2-hydroxyheptane
EINECS	Contact for details

Quality Control

Our (S)-(-)-1,1,1-Trifluoroheptan-2-Ol is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including chiral purity determination by HPLC and GC, to ensure it meets the stringent requirements for advanced synthetic applications. A Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profile is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at a controlled room temperature (15-25°C). Keep away from incompatible materials such as strong bases and fluorides. For long-term storage under inert atmosphere, please contact us for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.