Description

n-Methoxy-n-Methyl(Triphenyl-Phosphoranylidene)Acetamide is a specialized Wittig-Horner type reagent, widely recognized for its role as a key synthon in organic synthesis. This compound is valued for its ability to facilitate the efficient conversion of aldehydes and ketones into α,β-unsaturated amides and esters, a critical step in constructing complex molecular frameworks. It is an essential building block for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-purity intermediates for complex synthesis.

Application

• Pharmaceutical Intermediate Synthesis: A crucial reagent for constructing α,β-unsaturated carbonyl derivatives, key motifs in active pharmaceutical ingredients (APIs).
• Agrochemical Production: Used in the synthesis of complex molecules for crop protection agents and herbicides.
• Advanced Material Development: Employed in the creation of specialty polymers and functional organic materials.
• Academic & Industrial R&D: A versatile tool in organic chemistry laboratories for method development and novel compound synthesis.
• Peptide Mimetics & Bioactive Molecule Construction: Facilitates the introduction of dehydroamino acid units and other unsaturated amide functionalities.
• Fine Chemical Manufacturing: Serves as a high-value intermediate in the production of flavors, fragrances, and other specialty chemicals.

Basic Information

Product Name	n-Methoxy-n-Methyl(Triphenyl-Phosphoranylidene)Acetamide
CAS No.	129986-67-0
Molecular Formula	C22H22NO2P
Molecular Weight	363.39 g/mol
Synonyms	N-Methoxy-N-methyl-2-oxo-2-(triphenyl-λ5-phosphanylidene)acetamide; (Methoxy(methyl)carbamoyl)methylidenetriphenylphosphorane; Weiler's Reagent; N-Methoxy-N-methyl-2-(triphenylphosphoranylidene)acetamide; Acetamide, N-methoxy-N-methyl-2-oxo-2-(triphenylphosphoranylidene)-; WMMA; Horner-Wadsworth-Emmons Reagent (Acetamide variant)
EINECS	Contact for details

Quality Control

Our n-Methoxy-n-Methyl(Triphenyl-Phosphoranylidene)Acetamide is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high chemical purity suitable for demanding synthetic applications. All products undergo rigorous analytical testing, including HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic and moisture-sensitive nature, the container must be kept tightly sealed under an inert atmosphere (argon or nitrogen) after opening to prevent degradation and oxidation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to pale yellow crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.