Description

Triethylammonium 1,2-Di-o-Hexadecyl-Glycero-3-H-Phosphonate is a high-purity synthetic phospholipid derivative, specifically a phosphonate analog of phosphatidic acid. This compound is a critical building block and key intermediate in advanced lipid research and the development of novel drug delivery systems. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and specialty chemical sectors for creating liposomal formulations, lipid nanoparticles (LNPs), and other biomimetic membranes.

Application

• Lipid Nanoparticle (LNP) Formulation: A key ionizable cationic lipid component for mRNA and siRNA delivery systems.
• Liposome Production: Used as a functionalized phospholipid to modify surface charge and stability of liposomes for targeted drug delivery.
• Biomimetic Membrane Research: Serves as a model compound for studying membrane biophysics, protein-lipid interactions, and signal transduction.
• Gene Therapy: An essential raw material in the synthesis of non-viral vectors for gene therapy applications.
• Pharmaceutical Intermediates: Acts as a sophisticated intermediate in the synthesis of more complex therapeutic lipids and prodrugs.
• Diagnostic Reagents: Can be used in the development of diagnostic assays and imaging agents that target cellular membranes.

Basic Information

Product Name	Triethylammonium 1,2-Di-o-Hexadecyl-Glycero-3-H-Phosphonate
CAS No.	129983-81-9
Molecular Formula	C44H92NO6P
Molecular Weight	762.18 g/mol
Synonyms	1,2-Di-O-hexadecyl-sn-glycero-3-phosphonate triethylammonium salt; DHGP triethylammonium salt; 1,2-Dihexadecyl-rac-glycero-3-phosphonate triethylammonium salt; Glycerol 1,2-dihexadecyl ether 3-phosphonate triethylammonium salt; Phosphatidic acid phosphonate analog; Lipid phosphonate; Triethylammonium 1,2-dihexadecyl-glycerophosphonate
EINECS	Contact for details

Quality Control

Every batch of Triethylammonium 1,2-Di-o-Hexadecyl-Glycero-3-H-Phosphonate is manufactured and tested under strict quality management systems to ensure consistency and purity for sensitive research and GMP-grade applications. Our products undergo rigorous quality testing, including advanced chromatographic and spectroscopic methods, to ensure compliance with industry standards. Certificates of Analysis (COA) with detailed batch-specific results are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere (e.g., argon or nitrogen) due to its hygroscopic and moisture-sensitive nature. For long-term storage, desiccate. Allow the sealed container to reach room temperature before opening to prevent condensation and moisture ingress.

Specification

Item	Specification
Appearance	White to off-white waxy solid or film
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.