Description

Propio-2,2-D2-Phenone is a deuterated derivative of propiophenone, specifically labeled at the 2,2-position, with the CAS registry number 129848-87-9. This compound serves as a critical stable isotope-labeled standard, providing unmatched precision for analytical methods in research and quality control. It is essential for scientists and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require high-fidelity internal standards for mass spectrometry, NMR spectroscopy, and metabolic studies.

Application

• Internal Standard for Mass Spectrometry (MS): Used as a quantitative reference standard in LC-MS and GC-MS analysis to ensure accurate measurement of propiophenone and related compounds in complex matrices.
• NMR Spectroscopy Solvent & Reagent: Acts as a deuterated solvent or a tracer in nuclear magnetic resonance studies to elucidate molecular structures and reaction mechanisms without signal interference.
• Pharmaceutical Research & Development: Employed in drug metabolism and pharmacokinetics (DMPK) studies as a stable isotope-labeled analog to track the fate of active pharmaceutical ingredients.
• Chemical Synthesis Intermediate: Serves as a specialized building block for synthesizing more complex deuterated molecules for research and industrial applications.
• Quality Control & Method Validation: Critical for developing and validating analytical methods in compliance with GLP and GMP guidelines, ensuring reliability and reproducibility.
• Environmental and Forensic Analysis: Utilized as a high-purity standard for detecting and quantifying trace levels of target analytes in environmental samples or forensic investigations.

Basic Information

Product Name	Propio-2,2-D2-Phenone
CAS No.	129848-87-9
Molecular Formula	C9H8D2O
Molecular Weight	136.20 g/mol
Synonyms	Propiophenone-2,2-d2; 1-Phenyl-1-propanone-2,2-d2; 2,2-Dideuteriopropiophenone; Deuterated Propiophenone; Ethyl-d2 phenyl ketone; Phenylethyl-d2 ketone; (2,2-Dideuterioethyl) phenyl ketone; Benzyl methyl-d2 ketone
EINECS	Contact for details

Quality Control

Every batch of Propio-2,2-D2-Phenone is manufactured and tested under strict quality management systems. We guarantee high chemical and isotopic purity, with comprehensive testing including assay, isotopic enrichment (D atom %), and identification. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting compliance with customer specifications and relevant industry standards for research chemicals.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Due to its highly volatile nature, ensure containers are securely sealed when not in use to prevent evaporation and potential concentration changes.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 98.0%
Isotopic Purity (D atom %)	≥ 98.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.