Description

1-(tert-Butoxycarbonyl)-5-Chloroindole is a protected indole derivative, a crucial advanced intermediate in modern organic synthesis. Its core value lies in providing a versatile, reactive scaffold for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for medicinal chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries who require high-purity building blocks for drug discovery and API synthesis.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new active ingredients for crop protection products.
• Organic Synthesis Reagent: Serves as a versatile precursor for the preparation of more complex indole-based heterocycles and functionalized molecules.
• Material Science Research: Employed in the development of organic electronic materials and specialty polymers where the indole moiety is required.
• Academic & R&D Laboratories: A valuable tool for methodological studies and the exploration of new synthetic pathways in university and industrial research settings.

Basic Information

Product Name	1-(tert-Butoxycarbonyl)-5-Chloroindole
CAS No.	129822-48-6
Molecular Formula	C13H14ClNO2
Molecular Weight	251.71 g/mol
Synonyms	5-Chloro-1-Boc-indole; 1-Boc-5-Chloroindole; tert-Butyl 5-Chloro-1H-indole-1-carboxylate; 5-Chloroindole-1-carboxylic acid tert-butyl ester; 1H-Indole-1-carboxylic acid, 5-chloro-, 1,1-dimethylethyl ester; Boc-5-Chloroindole; N-Boc-5-Chloroindole
EINECS	Contact for details

Quality Control

Our 1-(tert-Butoxycarbonyl)-5-Chloroindole is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all relevant specifications. Our quality commitment aligns with the standards expected for advanced pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider storing under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.