Description

(6-Phthalimidohexyl)Triphenylphosphonium Bromide is a specialized organophosphonium salt that serves as a versatile building block and reagent in advanced organic synthesis. Its molecular architecture, combining a phthalimide-protected amine linker with a triphenylphosphonium moiety, makes it particularly valuable for creating targeted delivery systems and functional materials. This compound is essential for researchers and process development chemists in the pharmaceutical, agrochemical, and materials science sectors seeking to develop novel active compounds or modify biomolecules.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of mitochondrially-targeted drug conjugates and prodrugs, leveraging the triphenylphosphonium cation for enhanced cellular uptake.
• Peptide & Protein Modification: Used to introduce lipophilic cations or fluorescent tags via the reactive phthalimido group, enabling studies on cellular trafficking and localization.
• Polymer & Dendrimer Synthesis: Acts as a functional monomer or cross-linking agent for creating specialty polymers with cationic or stimuli-responsive properties.
• Catalyst & Ligand Preparation: Serves as a precursor for synthesizing novel phosphine ligands used in transition metal catalysis for fine chemical production.
• Antioxidant Research: Component in the development of synthetic antioxidants designed to accumulate in specific cellular compartments.
• Material Science: Building block for functionalizing surfaces or nanoparticles to impart specific chemical or biological activity.

Basic Information

Product Name	(6-Phthalimidohexyl)Triphenylphosphonium Bromide
CAS No.	129789-59-9
Molecular Formula	C33H31BrN2O2P
Molecular Weight	607.49 g/mol
Synonyms	N-(6-Triphenylphosphoniohexyl)phthalimide bromide; 6-Phthalimidohexyltriphenylphosphonium bromide; PPh3+C6H12NPhth Br-; TPPM-Phth; MITO-PHTH; Triphenyl(6-phthalimidohexyl)phosphonium bromide; N-(6-(Triphenylphosphonio)hexyl)phthalimide bromide
EINECS	Contact for details

Quality Control

Every batch of (6-Phthalimidohexyl)Triphenylphosphonium Bromide is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure identity, purity, and consistency for your critical research and development projects. A detailed Certificate of Analysis (COA), including results from NMR, HPLC, and elemental analysis, is supplied with each shipment to guarantee compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when possible to maintain stability and purity. Keep the container tightly sealed in a desiccator for long-term storage.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.