Description

Boc-α-Allyl-L-Alanine CAS NO 129786-68-1 is a protected, non-proteinogenic amino acid derivative featuring an N-terminal tert-butoxycarbonyl (Boc) group and an allyl side chain. This compound is a crucial building block in solid-phase peptide synthesis (SPPS), enabling the controlled introduction of unique structural motifs and facilitating subsequent orthogonal deprotection strategies. It is primarily utilized by research scientists and process chemists in the pharmaceutical, biotechnology, and advanced materials sectors for developing novel peptide-based therapeutics, diagnostic agents, and specialty polymers.

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of complex peptide drugs, including enzyme inhibitors and receptor agonists/antagonists.
• Peptide Research & Development: Used in academic and industrial R&D for constructing peptide libraries and exploring structure-activity relationships (SAR).
• Conjugation Chemistry: The allyl group serves as a handle for site-specific bioconjugation via thiol-ene "click" chemistry or other coupling reactions.
• Material Science: Incorporation into specialty polymers and biomaterials to impart specific chemical functionality or cross-linking capabilities.
• Chemical Biology Probes: Synthesis of labeled or modified peptides used as probes to study biological processes and protein interactions.

Basic Information

Product Name	Boc-α-Allyl-L-Alanine
CAS No.	129786-68-1
Molecular Formula	C11H19NO4
Molecular Weight	229.27 g/mol
Synonyms	(S)-2-((tert-Butoxycarbonyl)amino)pent-4-enoic acid; N-(tert-Butoxycarbonyl)-L-2-amino-4-pentenoic acid; Boc-L-2-Amino-4-pentenoic acid; Boc-Allylglycine; Boc-2-Amino-4-pentenoic acid; N-Boc-L-2-Amino-4-pentenoic acid; Boc-α-Allyl-L-Ala-OH
EINECS	Contact for details

Quality Control

Our Boc-α-Allyl-L-Alanine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for advanced synthetic applications. Certificates of Analysis (COA) detailing purity, chiral purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. This material is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider desiccant or inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% (L-isomer)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.