Description

Bicyclo[2.2.1]Heptane-2,7-Diol, 7-Acetate, [1S-(Exo,Anti)]- (9Ci) is a high-purity, stereochemically defined chiral building block and pharmaceutical intermediate. This compound is valued for its rigid bicyclic framework, which is instrumental in imparting specific three-dimensional structure and stability to target molecules. It is primarily sought by research institutions and manufacturers in the pharmaceutical and advanced materials sectors for applications in asymmetric synthesis and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key chiral synthon for the research and development of new active pharmaceutical ingredients (APIs), particularly in areas requiring specific stereochemical control.
• Asymmetric Synthesis: Used as a precursor or auxiliary in catalytic and stoichiometric asymmetric reactions to construct complex molecular architectures.
• Ligand and Catalyst Development: Serves as a core structure for designing novel chiral ligands and organocatalysts used in enantioselective transformations.
• Advanced Material Research: Employed in the synthesis of specialty polymers and functional materials where the norbornane skeleton provides thermal stability and rigidity.
• Fine Chemical Synthesis: Utilized in the multi-step synthesis of complex natural products, agrochemicals, and other high-value fine chemicals.
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry and for probing structure-activity relationships (SAR).

Basic Information

Product Name	Bicyclo[2.2.1]Heptane-2,7-Diol, 7-Acetate, [1S-(Exo,Anti)]- (9Ci)
CAS No.	129760-90-3
Molecular Formula	C9H14O3
Molecular Weight	170.21 g/mol
Synonyms	(1S,2R,4S)-Bicyclo[2.2.1]heptane-2,7-diol 7-acetate; (1S,2R,4S)-7-(Acetyloxy)bicyclo[2.2.1]heptane-2-ol; endo-2-Hydroxy-exo-7-acetoxynorbornane (stereospecific); (1S,2R,4S)-7-Acetoxynorbornan-2-ol; exo,anti-7-Acetoxy-2-norbornanol; Chiral Norbornane Diol Monoacetate; [1S-(exo,anti)]-7-Acetoxybicyclo[2.2.1]heptan-2-ol
EINECS	Contact for details

Quality Control

Our production of this chiral intermediate adheres to strict quality management protocols to ensure batch-to-batch consistency and high chemical purity. Quality is verified through comprehensive analytical techniques including HPLC, chiral GC/HPLC, and NMR to confirm identity, enantiomeric excess, and impurity profiles. A detailed Certificate of Analysis (COA) is provided with each shipment, documenting all critical specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). Keep away from heat sources and incompatible materials. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC/GC)	≥ 99.0% ee
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.