Description

2-Acetamido-2,4-Dideoxy-4-Fluoro-α-D-Glucopyranose is a fluorinated carbohydrate derivative, a key intermediate in the synthesis of novel bioactive compounds. Its value lies in its role as a versatile building block for developing fluorinated pharmaceuticals and diagnostic agents, where the fluorine atom can significantly alter metabolic stability and binding affinity. This high-purity intermediate is essential for research and development laboratories and production facilities in the pharmaceutical, biotechnology, and fine chemical sectors focused on next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of fluorinated nucleoside analogs and glycosidase inhibitors.
• Antiviral Drug Development: Used in research for creating novel antiviral agents, particularly targeting viral enzymes.
• Glycobiology Research: Serves as a tool compound for studying enzyme mechanisms and carbohydrate-protein interactions.
• PET Tracer Synthesis: Potential building block for the development of Positron Emission Tomography (PET) imaging agents containing fluorine-18.
• Medicinal Chemistry: Enables structure-activity relationship (SAR) studies by introducing fluorine at specific positions on sugar moieties.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex, high-value specialty chemicals.

Basic Information

Product Name	2-Acetamido-2,4-Dideoxy-4-Fluoro-α-D-Glucopyranose
CAS No.	129728-87-6
Molecular Formula	C8H14FNO5
Molecular Weight	223.20 g/mol
Synonyms	4-Fluoro-2-acetamido-2,4-dideoxy-D-glucopyranose; 2-Acetamido-2,4-dideoxy-4-fluoro-D-glucose; 4-Fluoro-N-acetyl-D-glucosamine derivative; 4-Fluoro-2-deoxy-2-acetamido-D-glucose; 2-Acetamido-4-fluoro-2,4-dideoxy-D-glucopyranose; 4-Fluoro-GlcNAc; Fluorinated N-Acetylglucosamine Intermediate; 129728-87-6
EINECS	Contact for details

Quality Control

Our 2-Acetamido-2,4-Dideoxy-4-Fluoro-α-D-Glucopyranose is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and chiral analysis to ensure stereochemical integrity. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to support your quality and regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Specific Rotation	Contact for details
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.