Description

1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-, 1,1-Dimethylethyl Ester is a high-purity, specialized nitroindole derivative serving as a critical synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active compounds.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Research: Used in the development of new active ingredients for crop protection products.
• Chemical Biology Probes: Serves as a precursor for labeled compounds used in mechanism-of-action studies and target identification.
• Material Science: Potential monomer or precursor for specialty polymers and advanced organic materials.
• Academic & Contract Research: Essential for methodological development and exploratory synthesis in university and CRO laboratories.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-, 1,1-Dimethylethyl Ester
CAS No.	129488-25-1
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	tert-Butyl 2,3-dihydro-5-nitro-1H-indole-1-carboxylate; 5-Nitro-2,3-dihydroindole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-nitroindoline; 1-Boc-5-nitroindoline; Boc-5-nitroindoline; 5-Nitroindoline-1-carboxylic acid tert-butyl ester; 2,3-Dihydro-5-nitro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid, 2,3-Dihydro-5-Nitro-, 1,1-Dimethylethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical quality attributes are available upon request, supporting compliance with research and cGMP guidelines where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.