Description

1-Boc-5-Amino-Indazole is a high-purity, protected indazole derivative widely used as a critical pharmaceutical intermediate. Its value lies in providing a versatile and stable amine-protected scaffold for the synthesis of complex bioactive molecules, particularly in drug discovery and development. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries seeking to build novel heterocyclic compounds.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of kinase inhibitors, anticancer agents, and other small molecule therapeutics.
• Agrochemical Research: Used in the development of novel pesticides and herbicides due to the bioactive indazole core.
• Chemical Biology: Serves as a precursor for probe and ligand synthesis in target identification and validation studies.
• Peptidomimetics: Employed in the construction of peptide-like molecules with enhanced stability and bioavailability.
• Material Science: Potential monomer or precursor for advanced polymers and functional materials.
• Custom Synthesis: A starting material for contract research organizations (CROs) and CDMOs for client-specific molecule assembly.

Basic Information

Product Name	1-Boc-5-Amino-Indazole
CAS No.	129488-10-4
Molecular Formula	C₁₂H₁₅N₃O₂
Molecular Weight	233.27 g/mol
Synonyms	5-Amino-1-[(tert-butoxy)carbonyl]-1H-indazole; tert-Butyl 5-amino-1H-indazole-1-carboxylate; 1H-Indazole-1-carboxylic acid, 5-amino-, 1,1-dimethylethyl ester; 5-Amino-1-Boc-indazole; 1-Boc-5-aminoindazole; Boc-5-Aminoindazole; 5-Aminoindazole-1-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our 1-Boc-5-Amino-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high chemical purity and identity. We provide Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality commitment aligns with cGMP principles for pharmaceutical intermediates, ensuring reliability for your critical research and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.