Description

N-(1)-Boc-5-Nitro-Indazole is a protected indazole derivative, a crucial building block in modern organic synthesis. Its primary value lies in serving as a versatile synthetic intermediate for the development of complex pharmaceutical compounds and advanced materials. This high-purity intermediate is essential for research and production in the pharmaceutical, agrochemical, and specialty chemical industries, where precise molecular construction is required.

Application

• Pharmaceutical Intermediate: Key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used as a core scaffold for developing novel pesticides and herbicides with specific modes of action.
• Chemical Biology Probes: Employed in the creation of molecular probes for studying enzyme function and cellular signaling pathways.
• Material Science: Serves as a monomer or functionalizing agent in the synthesis of specialty polymers and advanced organic materials.
• Academic & Contract Research: A valuable reagent for medicinal chemistry programs and process development in academic and CRO/CMO settings.

Basic Information

Product Name	N-(1)-Boc-5-Nitro-Indazole
CAS No.	129488-09-1
Molecular Formula	C₁₂H₁₃N₃O₄
Molecular Weight	263.25 g/mol
Synonyms	1-Boc-5-Nitro-1H-indazole; tert-Butyl 5-nitro-1H-indazole-1-carboxylate; 5-Nitro-1H-indazole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-5-nitro-1H-indazole; Boc-5-Nitroindazole; N-Boc-5-nitroindazole; 5-Nitroindazole-1-N-Boc
EINECS	Contact for details

Quality Control

Our N-(1)-Boc-5-Nitro-Indazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with each shipment, detailing all specifications and test results to ensure traceability and compliance with your research or production requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Off-white to light yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.