Description

6-Amino-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is a protected indoline derivative that serves as a critical synthetic intermediate in advanced organic chemistry. Its primary value lies in providing a versatile, nitrogen-containing scaffold with orthogonal protecting groups, enabling the efficient synthesis of complex heterocyclic compounds. This building block is essential for researchers and manufacturers in the pharmaceutical and agrochemical industries, particularly for developing new active pharmaceutical ingredients (APIs) and crop protection agents.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of indole-based drug candidates, including kinase inhibitors, serotonin receptor modulators, and other bioactive molecules.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides that leverage the indoline core structure.
• Organic Synthesis Building Block: Employed in medicinal chemistry for parallel synthesis and combinatorial chemistry to create diverse molecular libraries.
• Material Science Research: Potential monomer or precursor for functional polymers and advanced organic materials.
• Academic & R&D: Serves as a standard reagent in university and contract research organization (CRO) laboratories for method development and novel route exploration.

Basic Information

Product Name	6-Amino-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester
CAS No.	129488-00-2
Molecular Formula	C13H18N2O2
Molecular Weight	234.30 g/mol
Synonyms	1H-Indole-1-carboxylic acid, 6-amino-2,3-dihydro-, 1,1-dimethylethyl ester; tert-Butyl 6-amino-2,3-dihydro-1H-indole-1-carboxylate; 6-Aminoindoline-1-carboxylic acid tert-butyl ester; Boc-6-Aminoindoline; 1-Boc-6-aminoindoline; 6-Amino-N-Boc-indoline; 129488-00-2; tert-Butyl 6-aminoindoline-1-carboxylate
EINECS	Contact for details

Quality Control

Our 6-Amino-2,3-Dihydro-Indole-1-Carboxylic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is easily oxidized and should be handled under an inert atmosphere for long-term storage. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.