Description

1H-Indole-1-Carboxylic Acid,2,3-Dihydro-6-Nitro-,1,1-Dimethylethyl Ester is a specialized nitro-substituted indole derivative that serves as a valuable synthetic intermediate in advanced organic chemistry. This compound is critical for researchers and manufacturers requiring a protected, reactive scaffold for constructing complex heterocyclic molecules. It is primarily utilized in pharmaceutical research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel indole-based drug candidates targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Research: Used in the development of new pesticides and herbicides, leveraging its nitro and ester functional groups for structural modification.
• Organic Synthesis: Serves as a versatile precursor for palladium-catalyzed cross-coupling reactions, such as Suzuki or Heck reactions, to create complex molecular architectures.
• Material Science: Potential intermediate in the synthesis of organic semiconductors and functional dyes due to the indole core's electronic properties.
• Academic & R&D: Employed in university and institutional laboratories for methodological studies and the exploration of new chemical transformations.

Basic Information

Product Name	1H-Indole-1-Carboxylic Acid,2,3-Dihydro-6-Nitro-,1,1-Dimethylethyl Ester
CAS No.	129487-99-6
Molecular Formula	C14H16N2O4
Molecular Weight	276.29 g/mol
Synonyms	tert-Butyl 2,3-dihydro-6-nitro-1H-indole-1-carboxylate; 6-Nitro-2,3-dihydro-1H-indole-1-carboxylic acid tert-butyl ester; 1-(tert-Butoxycarbonyl)-6-nitroindoline; 1-Boc-6-nitroindoline; Boc-6-nitroindoline; 6-Nitroindoline-1-carboxylic acid tert-butyl ester; 2,3-Dihydro-6-nitro-1H-indole-1-carboxylic acid 1,1-dimethylethyl ester
EINECS	Contact for details

Quality Control

Our 1H-Indole-1-Carboxylic Acid,2,3-Dihydro-6-Nitro-,1,1-Dimethylethyl Ester is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference standard
Purity (HPLC)	≥ 97.0%
Melting Point	Contact for details
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.