Description

1-Propanone, 1-(4-Thiazolyl)- is a specialized organic compound featuring a thiazole ring, a heterocyclic structure of significant interest in synthetic chemistry. This compound serves as a valuable building block and key intermediate for the development of more complex molecules, particularly in the pharmaceutical and agrochemical sectors. Its unique structure makes it essential for researchers and manufacturers engaged in the synthesis of active ingredients, functional materials, and novel chemical entities.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of active pharmaceutical ingredients (APIs), especially those containing thiazole moieties for therapeutic applications.
• Agrochemical Synthesis: Used in the research and production of advanced pesticides, herbicides, and fungicides where the thiazole ring contributes to biological activity.
• Material Science Research: Serves as a monomer or functionalizing agent in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Research & Development: Employed as a versatile scaffold in medicinal chemistry for hit-to-lead optimization and structure-activity relationship (SAR) studies.
• Fine Chemical Production: Acts as an intermediate in the multi-step synthesis of dyes, pigments, and other high-value specialty chemicals.

Basic Information

Product Name	1-Propanone, 1-(4-Thiazolyl)-
CAS No.	129425-74-7
Molecular Formula	C6H7NOS
Molecular Weight	141.19 g/mol
Synonyms	1-(1,3-Thiazol-4-yl)propan-1-one; 4-Propanoythiazole; 1-(Thiazol-4-yl)propan-1-one; 4-Acetylthiazole (common misnomer, structurally related); 4-Thiazolyl ethyl ketone; 1-(4-Thiazolyl)-1-propanone; 4-Propanoyl-1,3-thiazole; 1-(1,3-Thiazol-4-yl)-1-propanone
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and purity. Our production of 1-Propanone, 1-(4-Thiazolyl)- adheres to strict in-process controls, with final product release contingent on comprehensive analytical verification. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in opaque packaging or amber glass.

Specification

Item	Specification
Appearance	Light yellow to yellow solid or liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.