Description

Methyl 3-Amino-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylate is a high-value heterocyclic building block and advanced pharmaceutical intermediate. This compound matters for its role as a critical precursor in the synthesis of complex molecules, particularly in medicinal chemistry and materials science. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and specialty chemical industries for creating novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in therapeutic areas targeting CNS disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides, leveraging the thiophene scaffold for bioactivity.
• Organic Electronic Materials: Serves as a precursor for conjugated polymers and small molecules used in organic light-emitting diodes (OLEDs) and organic photovoltaics (OPVs).
• Dye and Pigment Manufacturing: Intermediate for producing specialized heterocyclic dyes with specific light-absorption properties.
• Chemical Research & Development: A versatile synthon in academic and industrial labs for exploring new chemical reactions and constructing complex molecular architectures.
• Ligand and Catalyst Development: Potential precursor for creating novel ligands used in asymmetric catalysis and metal-organic frameworks (MOFs).

Basic Information

Product Name	Methyl 3-Amino-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylate
CAS No.	129332-45-2
Molecular Formula	C8H8N2O2S2
Molecular Weight	228.29 g/mol
Synonyms	Methyl 3-amino-4-cyano-5-(methylthio)thiophene-2-carboxylate; 3-Amino-4-cyano-5-(methylthio)thiophene-2-carboxylic acid methyl ester; 2-Thiophenecarboxylic acid, 3-amino-4-cyano-5-(methylthio)-, methyl ester; Methyl 3-amino-5-(methylthio)-4-cyanothiophene-2-carboxylate; 129332-45-2; 5-(Methylthio)-3-amino-4-cyanothiophene-2-carboxylic acid methyl ester
EINECS	Contact for details

Quality Control

Our Methyl 3-Amino-4-Cyano-5-(Methylthio)Thiophene-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and consistent chemical identity. Certificates of Analysis (COA) detailing purity, impurities, and physical characteristics are provided with each shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	Light yellow to yellow crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.