Description

3(2H)-Thiophenone, 2-Chlorodihydro-2-Methyl- is a specialized sulfur-containing heterocyclic compound with a chlorinated, saturated ketone structure. This chemical serves as a valuable advanced pharmaceutical intermediate and a versatile building block in organic synthesis, enabling the construction of complex molecular architectures. It is primarily sought after by R&D chemists and process development teams in the pharmaceutical, agrochemical, and material science industries for the development of novel active ingredients and functional molecules.

Application

• Pharmaceutical Intermediate: A key synthon in the research and synthesis of novel drug candidates, particularly those targeting the central nervous system or possessing anti-infective properties.
• Agrochemical Synthesis: Used in the development of new herbicides, fungicides, and insecticides, leveraging its reactive chloromethyl ketone moiety.
• Organic Synthesis Building Block: Employed in cyclization reactions, nucleophilic substitutions, and as a precursor for more complex thiophene derivatives.
• Material Science Research: Investigated as a monomer or precursor for specialty polymers and organic electronic materials due to the thiophene backbone.
• Chemical Biology Probes: Utilized in the design of activity-based probes and molecular tags for studying biological systems.

Basic Information

Product Name	3(2H)-Thiophenone, 2-Chlorodihydro-2-Methyl-
CAS No.	129314-85-8
Molecular Formula	C5H7ClOS
Molecular Weight	150.62 g/mol
Synonyms	2-Chloro-2-methyl-2,3-dihydrothiophen-3-one; 2-Chloro-2-methyl-dihydro-thiophen-3-one; 2-Methyl-2-chloro-2,5-dihydrothiophen-3-one; 2-Chloro-2-methyl-4,5-dihydro-3(2H)-thiophenone; 2-Chloro-2-methyl-2,3-dihydrothiophen-3(2H)-one; 2-Chloro-2-methyl-δ³-thiolenone; 2-Chloro-2-methyl-4,5-dihydrothiophen-3(2H)-one
EINECS	Contact for details

Quality Control

We maintain a rigorous quality management system to ensure batch-to-batch consistency and high purity. Our products undergo comprehensive analytical testing, including HPLC, GC, NMR, and IR spectroscopy. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment. We support development and scale-up with custom synthesis and purification services to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Recommended storage temperature is between 2°C and 8°C for long-term stability. Keep away from strong bases and reducing agents. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.