Description

6-Fluoro-1H-Indazole-3-Carboxylic Acid is a high-purity fluorinated indazole derivative serving as a critical building block in advanced organic synthesis. This compound is valued for its role in constructing complex molecular architectures, particularly in the development of active pharmaceutical ingredients (APIs) and agrochemicals. It is essential for research and production chemists in the pharmaceutical, agrochemical, and specialty chemical industries seeking to introduce the indazole scaffold with a carboxylic acid handle and fluorine substituent.

Application

• Pharmaceutical Intermediate: A key synthon for the research and development of novel drug candidates, particularly kinase inhibitors and other small molecule therapeutics.
• Agrochemical Synthesis: Used in the creation of advanced herbicides, fungicides, and pesticides where the fluorinated indazole core enhances biological activity and stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and library synthesis.
• Material Science Precursor: Potential use in the synthesis of organic ligands for catalysts or advanced functional materials.
• Bioconjugation & Probe Development: The carboxylic acid group allows for coupling reactions, useful in creating biochemical probes and diagnostic agents.

Basic Information

Product Name	6-Fluoro-1H-Indazole-3-Carboxylic Acid
CAS No.	129295-30-3
Molecular Formula	C8H5FN2O2
Molecular Weight	180.14 g/mol
Synonyms	6-Fluoro-1H-indazole-3-carboxylic acid; 6-Fluoroindazole-3-carboxylic acid; 3-Carboxy-6-fluoroindazole; 129295-30-3; 6-Fluoro-1H-indazol-3-carboxylic acid; 6-Fluoro-3-indazolecarboxylic acid; 6-Fluoroindazole-3-carboxylic acid (1H-indazole-3-carboxylic acid, 6-fluoro-)
EINECS	Contact for details

Quality Control

Our 6-Fluoro-1H-Indazole-3-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical intermediate applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; ensure containers are kept sealed to minimize exposure to atmospheric moisture and light.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.