Description

3-(6-Chloro-3-Pyridazinyl)-1H-Indole is a high-purity, advanced pharmaceutical intermediate characterized by its fused heterocyclic structure. This compound matters as a critical building block in modern medicinal chemistry, enabling the synthesis of novel active pharmaceutical ingredients (APIs) with targeted biological activity. It is primarily needed by research institutions and pharmaceutical manufacturers engaged in the development of new therapeutic agents, particularly within oncology and central nervous system (CNS) drug discovery pipelines.

Application

• Pharmaceutical Intermediate: A key precursor in the multi-step synthesis of novel drug candidates and active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Serves as a core scaffold for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Biochemical Tool Compound: Used in vitro and in vivo to study biological pathways and validate novel therapeutic targets.
• Contract Research & Manufacturing (CRAM): Supplied to CDMOs for custom synthesis and process development services.
• Academic Research: Utilized in university and institutional labs for pioneering research in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	3-(6-Chloro-3-Pyridazinyl)-1H-Indole
CAS No.	129287-26-9
Molecular Formula	C12H8ClN3
Molecular Weight	229.66 g/mol
Synonyms	1H-Indole, 3-(6-chloro-3-pyridazinyl)-; 3-(6-Chloropyridazin-3-yl)-1H-indole; 6-Chloro-3-(1H-indol-3-yl)pyridazine; 129287-26-9; 3-(6-Chloro-3-pyridazinyl)indole; 3-(6-Chloro-pyridazin-3-yl)-1H-indole
EINECS	Contact for details

Quality Control

Our 3-(6-Chloro-3-Pyridazinyl)-1H-Indole is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide full traceability and Certificates of Analysis (COA) are available for every shipment, confirming compliance with customer specifications and current Good Manufacturing Practice (cGMP) principles where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The material should be kept under an inert atmosphere for long-term storage to ensure stability. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.