Description

Lobetyolin CAS NO 129277-38-9 is a bioactive polyacetylene glycoside, a key marker compound derived from plants such as *Codonopsis pilosula*. This compound is valued for its significant pharmacological potential and serves as a critical reference standard for quality control in herbal medicine and natural product research. It is essential for researchers and manufacturers in the pharmaceutical, nutraceutical, and botanical extract industries who require high-purity, well-characterized compounds for analytical and development purposes.

Application

• Pharmaceutical Reference Standard: Used as a certified reference material (CRM) for the quantitative and qualitative analysis of *Codonopsis* species and related herbal products.
• Herbal Medicine Quality Control: Serves as a key marker compound in HPLC and LC-MS methods to authenticate and standardize extracts of Radix Codonopsis (Dangshen).
• Pharmacological Research: Employed in in-vitro and in-vivo studies to investigate potential bioactivities, including immunomodulatory, anti-fatigue, and gastroprotective effects.
• Nutraceutical Development: Used in the formulation and standardization of high-quality dietary supplements and functional food ingredients.
• Academic Research: A vital tool for phytochemistry, natural product isolation, and structural elucidation studies in university and institutional laboratories.
• Cosmeceutical Applications: Investigated for potential use in skincare formulations for its purported antioxidant and anti-inflammatory properties.

Basic Information

Product Name	Lobetyolin
CAS No.	129277-38-9
Molecular Formula	C₂₀H₂₈O₈
Molecular Weight	396.43 g/mol
Synonyms	Lobetyolin; Lobetyol; (2R,3S,4S,5R,6S)-2-(Hydroxymethyl)-6-[(2E,8E,10E)-tetradeca-2,8,10-trien-4,6-diyn-1-yl]oxy]oxane-3,4,5-triol; Codonopsis Pilosula Polyacetylene Glycoside; Dangshen Polyacetylene
EINECS	Contact for details

Quality Control

Our Lobetyolin is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, IR and MS for structural confirmation, and residual solvent analysis. We provide Certificates of Analysis (COA) with detailed chromatographic data, ensuring traceability and compliance with research-grade standards. Our quality commitment supports your need for reliable and consistent reference materials.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 2.0 %
Residue on Ignition	≤ 0.1 %
Heavy Metals	≤ 10 ppm
Residual Solvents	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.