Description

1-Bromo-3-[3-(Trifluoromethyl)Phenyl]Propane is a specialized organic building block featuring a bromopropyl chain linked to a trifluoromethyl-substituted benzene ring. This compound is valued for its unique combination of a reactive alkyl halide handle and the lipophilic, electron-withdrawing trifluoromethyl group, making it a versatile intermediate in advanced synthesis. It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical and agrochemical industries for constructing complex molecules, particularly in lead optimization and the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of drug candidates, especially those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced herbicides, fungicides, and insecticides where the CF3 group enhances biological activity and environmental stability.
• Material Science Research: Serves as a precursor for monomers or ligands in the development of specialty polymers, liquid crystals, and organic electronic materials.
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes and tags for studying biological systems and protein interactions.
• Cross-Coupling Reactions: Acts as an electrophilic coupling partner in palladium-catalyzed reactions (e.g., Suzuki, Heck) to introduce the 3-(trifluoromethyl)benzyl moiety into complex structures.

Basic Information

Product Name	1-Bromo-3-[3-(Trifluoromethyl)Phenyl]Propane
CAS No.	129254-76-8
Molecular Formula	C10H10BrF3
Molecular Weight	267.09 g/mol
Synonyms	3-(3-Bromopropyl)-α,α,α-trifluorotoluene; 1-Bromo-3-(3-trifluoromethylphenyl)propane; 3-(3-Trifluoromethylphenyl)propyl bromide; m-(Trifluoromethyl)phenethyl bromide; (3-Bromopropyl)-3-(trifluoromethyl)benzene; 3'-Trifluoromethylphenpropyl bromide; 3-(3-Bromopropyl)benzotrifluoride
EINECS	Contact for details

Quality Control

Our production of 1-Bromo-3-[3-(Trifluoromethyl)Phenyl]Propane adheres to strict quality management protocols to ensure batch-to-batch consistency and high purity for sensitive synthetic applications. Each lot is characterized using advanced analytical techniques including GC, HPLC, NMR, and IR spectroscopy. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment, supporting your regulatory and quality documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. Due to its light-sensitive nature, containers should be kept in amber glass or opaque packaging during storage.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (GC/HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.