Description

1-(3-Bromo-Propyl)-2-Fluoro-Benzene is a high-purity fluorinated and brominated aromatic building block of significant importance in advanced organic synthesis. Its bifunctional halogenated structure makes it a versatile intermediate for constructing complex molecular architectures. This compound is primarily sought after by research institutions and manufacturers in the pharmaceutical and agrochemical sectors for developing novel active ingredients and fine chemicals.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly those requiring fluorinated and brominated aromatic motifs for enhanced bioactivity and metabolic stability.
• Agrochemical Synthesis: Used in the research and production of advanced herbicides, fungicides, and insecticides, where the fluorine atom can improve lipophilicity and target binding.
• Ligand and Catalyst Development: Serves as a starting material for creating specialized ligands and organocatalysts used in asymmetric synthesis and cross-coupling reactions.
• Material Science Research: Employed in the development of novel organic electronic materials, liquid crystals, and functional polymers.
• Custom Synthesis and Contract Manufacturing: An essential building block for custom synthesis houses serving the life sciences and specialty chemicals industries.

Basic Information

Product Name	1-(3-Bromo-Propyl)-2-Fluoro-Benzene
CAS No.	129254-75-7
Molecular Formula	C9H10BrF
Molecular Weight	217.08 g/mol
Synonyms	2-Fluoro-1-(3-bromopropyl)benzene; 1-Bromo-3-(2-fluorophenyl)propane; 3-(2-Fluorophenyl)propyl bromide; (2-Fluorophenyl)propyl bromide; 2-Fluorobenzylpropyl bromide; 3-Bromopropyl-2-fluorobenzene; o-Fluoro-(3-bromopropyl)benzene
EINECS	Contact for details

Quality Control

Our 1-(3-Bromo-Propyl)-2-Fluoro-Benzene is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, GC, and NMR, to ensure high chemical purity and identity confirmation. We provide Certificates of Analysis (COA) with detailed specifications for trace metals, residual solvents, and related substances, supporting compliance with cGMP and ICH guidelines for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider under an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow clear liquid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.