Description

1-(4-Amino-3,5-Dichloro-Phenyl)-2-tert-Butyl-D9-Amino-Ethanone is a high-purity deuterated organic compound, specifically a tert-butylamino ethanone derivative with a dichloro-substituted aniline core. This compound is of significant value as a stable isotope-labeled intermediate or reference standard in advanced research and development. It is primarily needed by pharmaceutical and agrochemical R&D teams for applications in drug metabolism studies, pharmacokinetic research, and as a critical building block in the synthesis of novel active ingredients.

Application

• Pharmaceutical Research: Serves as a key deuterated intermediate in the synthesis of novel drug candidates, particularly for metabolic stability studies and the development of deuterium-labeled pharmaceuticals.
• Metabolite Identification & Pharmacokinetics (PK): Used as an internal standard in Liquid Chromatography-Mass Spectrometry (LC-MS) and Gas Chromatography-Mass Spectrometry (GC-MS) for accurate quantification and tracing of parent compounds and their metabolites in biological matrices.
• Agrochemical Development: Acts as a specialized building block for creating novel, labeled active ingredients or for conducting environmental fate and metabolism studies of pesticides and herbicides.
• Analytical Reference Standard: Provides a high-purity, chemically defined standard for method development, validation, and quality control in analytical laboratories.
• Isotope Labeling & Tracer Studies: The deuterium (D9) label makes it an essential tool for mechanistic studies in chemistry and biochemistry, tracking reaction pathways and molecular interactions.

Basic Information

Product Name	1-(4-Amino-3,5-Dichloro-Phenyl)-2-tert-Butyl-D9-Amino-Ethanone
CAS No.	129138-59-6
Molecular Formula	C12H7D9Cl2N2O
Molecular Weight	290.25 g/mol (approx.)
Synonyms	2-tert-Butylamino-1-(4-amino-3,5-dichlorophenyl)ethanone-d9; 1-(4-Amino-3,5-dichlorophenyl)-2-(tert-butylamino)ethanone-d9; 2-(tert-Butylamino)-1-(4-amino-3,5-dichlorophenyl)ethanone-d9; Deuterated 1-(4-Amino-3,5-dichloro-Phenyl)-2-tert-Butyl-Amino-Ethanone; D9-labeled tert-Butylamino Ethanone Derivative; 4-Amino-3,5-dichloro-α-[(1,1-dimethylethyl)amino]acetophenone-d9; (4-Amino-3,5-dichlorophenyl)[2-(tert-butylamino)-2-oxoethyl]d9-ketone
EINECS	Contact for details

Quality Control

Our 1-(4-Amino-3,5-Dichloro-Phenyl)-2-tert-Butyl-D9-Amino-Ethanone is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for chemical purity and isotopic enrichment, NMR for structural confirmation, and MS for identity verification. We provide comprehensive Certificates of Analysis (COA) detailing all specifications, including assay, deuterium enrichment level, and impurity profiles, ensuring traceability and compliance with research-grade standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability and purity. For long-term storage, consider inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Deuterium Enrichment (MS)	≥ 98 atom % D
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.