Description

5-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One is a high-value heterocyclic building block and key synthetic intermediate. This compound matters for its role in constructing complex molecular architectures, particularly in advanced pharmaceutical research and development. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and fine chemical industries for the synthesis of novel active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, cardiovascular diseases, and oncology.
• Agrochemical Research: Serves as a building block for developing new herbicides, fungicides, and insecticides with novel modes of action.
• Material Science: Used in the research and development of advanced organic materials, including organic semiconductors and liquid crystals.
• Chemical Biology: Employed as a scaffold or probe in the study of biological pathways and enzyme inhibition.
• Academic & Contract Research: A valuable reagent for universities and CROs (Contract Research Organizations) conducting synthetic methodology and medicinal chemistry projects.
• Fine Chemical Synthesis: Integral to the multi-step synthesis of complex, high-value specialty chemicals and dyes.

Basic Information

Product Name	5-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One
CAS No.	129075-59-8
Molecular Formula	C9H8ClNO
Molecular Weight	181.62 g/mol
Synonyms	5-Chloro-1,2,3,4-tetrahydroisoquinolin-1-one; 5-Chloro-3,4-dihydro-1(2H)-isoquinolinone; 5-Chloro-1-oxo-1,2,3,4-tetrahydroisoquinoline; 5-Chlorotetrahydroisoquinolin-1-one; 129075-59-8; 5-Chloro-3,4-dihydro-2H-isoquinolin-1-one
EINECS	Contact for details

Quality Control

Our 5-Chloro-3,4-Dihydro-2H-Isoquinolin-1-One is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and IR spectroscopy, to ensure it meets the high standards required for research and development applications. Certificates of Analysis (COA) with detailed chromatographic data are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). Keep away from incompatible materials such as strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.