Description

5-Amino-3,4-Dihydroisoquinolin-1(2H)-One Hydrochloride is a high-purity organic salt serving as a critical building block in advanced chemical synthesis. This compound matters for its role as a versatile intermediate in the development of complex pharmaceutical molecules and bioactive compounds. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and fine chemical industries for creating novel active ingredients and exploring new synthetic pathways.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of potential drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Agrochemical Synthesis: Used in the production of advanced pesticides and herbicides, leveraging its heterocyclic structure.
• Fine Chemical Manufacturing: Serves as a precursor for dyes, pigments, and other specialty chemicals requiring the isoquinoline scaffold.
• Academic & Contract Research: Essential for medicinal chemistry programs and process development in academic and contract research organizations (CROs).
• Chemical Biology Probes: Utilized in the design and synthesis of molecular probes for studying biological pathways and enzyme functions.

Basic Information

Product Name	5-Amino-3,4-Dihydroisoquinolin-1(2H)-One Hydrochloride
CAS No.	129075-52-1
Molecular Formula	C9H11ClN2O
Molecular Weight	198.65 g/mol
Synonyms	5-Amino-1,2,3,4-tetrahydroisoquinolin-1-one hydrochloride; 5-Amino-3,4-dihydro-1(2H)-isoquinolinone hydrochloride; 5-Amino-1,2,3,4-tetrahydroisoquinolin-1-one HCl; 5-Amino-1-oxo-1,2,3,4-tetrahydroisoquinoline hydrochloride; 129075-52-1; 5-Amino-3,4-dihydro-2H-isoquinolin-1-one hydrochloride
EINECS	Contact for details

Quality Control

Our 5-Amino-3,4-Dihydroisoquinolin-1(2H)-One Hydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) with detailed HPLC purity data are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.