Description

2-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci) is a specialized heterocyclic building block and key acylating agent. This compound matters for its role as a versatile intermediate in the synthesis of complex molecules, particularly in pharmaceutical and agrochemical research. It is primarily needed by R&D chemists and process development scientists in the life sciences sector for constructing novel active ingredients.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of novel drug candidates, particularly in kinase inhibitor and central nervous system (CNS) active compound research.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, leveraging the thiophene moiety for bioactivity.
• Material Science Precursor: Serves as a monomer or functionalization agent in the production of specialty polymers and conductive materials.
• Organic Synthesis Reagent: An essential acyl chloride for introducing the 4-methoxy-2-thiophenecarbonyl moiety into target molecules via amidation or esterification reactions.
• Ligand and Catalyst Development: Used to create complex ligands for metal catalysis and organocatalysts in asymmetric synthesis.

Basic Information

Product Name	2-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci)
CAS No.	128995-59-5
Molecular Formula	C6H5ClO2S
Molecular Weight	176.62 g/mol
Synonyms	4-Methoxy-2-thiophenecarbonyl chloride; 4-Methoxythiophene-2-carbonyl chloride; 2-Thenoyl chloride, 4-methoxy-; 4-Methoxy-2-thenoyl chloride; 4-Methoxythiophene-2-carboxylic acid chloride; 2-Carbonyl chloride-4-methoxythiophene; 4-Methoxy-thiophene-2-carboxylic acid chloride
EINECS	Contact for details

Quality Control

Our 2-Thiophenecarbonyl Chloride, 4-Methoxy- (9Ci) is produced under strict quality control protocols to ensure batch-to-batch consistency and high purity for research and development applications. We employ advanced analytical techniques including HPLC, GC, and NMR for identity confirmation and impurity profiling. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and related substances is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) to prevent degradation. Keep away from strong bases and oxidizing agents.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.