Description

Diethyl-4-1H-Indole-2,3-Dicarboxylate is a high-purity, versatile indole derivative serving as a critical synthetic intermediate in advanced organic chemistry. Its value lies in providing a functionalized indole core, enabling efficient construction of complex heterocyclic systems for research and development. This compound is essential for pharmaceutical chemists and agrochemical researchers developing novel active ingredients, as well as for academic institutions engaged in material science and medicinal chemistry projects.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of potential drug candidates, particularly those targeting central nervous system (CNS) disorders, anti-inflammatory agents, and kinase inhibitors.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and plant growth regulators that leverage the indole scaffold's biological activity.
• Material Science: Serves as a precursor for organic semiconductors, dyes, and photochromic materials due to its conjugated indole structure.
• Academic & R&D: Fundamental reagent in heterocyclic chemistry research for constructing complex indole-based libraries and studying structure-activity relationships (SAR).
• Fine Chemical Synthesis: Intermediate for producing specialty chemicals, including flavors, fragrances, and advanced polymer additives.

Basic Information

Product Name	Diethyl-4-1H-Indole-2,3-Dicarboxylate
CAS No.	128942-88-1
Molecular Formula	C15H17NO4
Molecular Weight	275.30 g/mol
Synonyms	Diethyl 4-1H-Indole-2,3-dicarboxylate; 2,3-Diethoxycarbonyl-4-1H-indole; 1H-Indole-2,3-dicarboxylic acid, 4-, diethyl ester; 4-Indole-2,3-dicarboxylic Acid Diethyl Ester; Diethyl 4-Indole-2,3-dicarboxylate; Ethyl 4-(ethoxycarbonyl)-1H-indole-2-carboxylate; 4-Carbethoxyindole-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Diethyl-4-1H-Indole-2,3-Dicarboxylate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods (NMR, IR). We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research or production specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP-like controls where applicable.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong bases and incompatible materials such as strong oxidizing agents. The container must be kept tightly sealed to prevent moisture absorption and contamination.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.