Description

Salbostatin CAS NO 128826-89-1 is a specialized chemical compound belonging to the statin class, known for its role as a potent and selective inhibitor of HMG-CoA reductase. This compound is of significant value in pharmaceutical research and development, particularly for studying cholesterol biosynthesis pathways and developing novel therapeutic agents. It is primarily needed by research institutions, pharmaceutical manufacturers, and biotechnology companies engaged in metabolic disorder research, cardiovascular drug discovery, and enzyme inhibition studies.

Application

• As a key reference standard in analytical method development and validation for statin-related pharmaceuticals.
• As a critical biochemical tool for in vitro and in vivo studies targeting the HMG-CoA reductase enzyme in metabolic research.
• For use in pharmaceutical R&D as a precursor or intermediate in the synthesis of novel cholesterol-lowering agents.
• In academic and industrial research focused on understanding atherosclerosis and lipid metabolism disorders.
• As a potent inhibitor in enzymatic assays to screen for other modulators of the mevalonate pathway.

Basic Information

Product Name	Salbostatin
CAS No.	128826-89-1
Molecular Formula	C25H39NO5
Molecular Weight	433.59 g/mol
Synonyms	Salbostatin; (3R,5R)-7-[(1S,2S,6S,8S,8aR)-6-Hydroxy-2-methyl-8-{[(2S)-2-methylbutanoyl]oxy}-1,2,6,7,8,8a-hexahydronaphthalen-1-yl]-3,5-dihydroxyheptanoic Acid; HMG-CoA Reductase Inhibitor; Compactin analogue; ML-236B analogue; L-645,164; Statin research compound.
EINECS	Contact for details

Quality Control

Our Salbostatin is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for research applications. The product undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods. A comprehensive Certificate of Analysis (COA) detailing all test results and specifications is provided with each batch to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider desiccants or inert atmosphere conditions.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.