Description

1H-Indol-5-Yl Methanesulfonate is a high-purity, functionalized indole derivative of significant interest in advanced organic synthesis. This compound serves as a versatile and critical building block for the development of complex molecules, particularly in the pharmaceutical and agrochemical sectors. It is essential for researchers and process chemists engaged in the synthesis of novel active pharmaceutical ingredients (APIs), heterocyclic compounds, and fine chemicals, where precise molecular architecture is paramount.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting central nervous system (CNS) disorders and other therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of new generation pesticides and herbicides that require specific indole-based scaffolds for bioactivity.
• Organic Synthesis Building Block: Employed in academic and industrial R&D for constructing complex heterocyclic frameworks and functionalized indole derivatives.
• Material Science Research: Investigated as a monomer or functional component in the development of advanced organic electronic materials and specialty polymers.
• Bioconjugation & Probe Development: Utilized in the creation of biochemical probes and labeling reagents due to its reactive methanesulfonate group.

Basic Information

Product Name	1H-Indol-5-Yl Methanesulfonate
CAS No.	128810-31-1
Molecular Formula	C10H11NO3S
Molecular Weight	225.26 g/mol
Synonyms	5-Indolyl methanesulfonate; 1H-Indol-5-yl methylsulfonate; Methanesulfonic acid 1H-indol-5-yl ester; Indol-5-yl methanesulfonate; 5-(Methylsulfonyloxy)indole; 5-Hydroxyindole methanesulfonate ester; 5-Methanesulfonoxyindole; 128810-31-1
EINECS	Contact for details

Quality Control

Every batch of 1H-Indol-5-Yl Methanesulfonate is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing batch-specific results are provided and available upon request to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive and easily oxidized; for long-term storage, consider maintaining under an inert atmosphere such as nitrogen or argon to preserve stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.