Description

Ethyl 6-Bromo-5-Methoxyindole-2-Carboxylate is a high-purity, versatile indole derivative serving as a critical building block in advanced organic synthesis. Its value lies in its functionalized indole core, which provides a strategic handle for constructing complex molecules, particularly in pharmaceutical research and development. This compound is essential for R&D chemists and process development scientists working in medicinal chemistry, agrochemicals, and material science.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly those targeting serotonin receptors and other neurological pathways.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Agrochemical Synthesis: Serves as a building block for developing new active ingredients with potential herbicidal or insecticidal properties.
• Material Science: A potential monomer or precursor for functional polymers and advanced organic electronic materials.
• Academic & Contract Research: Employed in university and CRO laboratories for methodological development and the synthesis of complex heterocyclic compounds.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	Ethyl 6-Bromo-5-Methoxyindole-2-Carboxylate
CAS No.	128593-40-8
Molecular Formula	C₁₂H₁₂BrNO₃
Molecular Weight	298.13 g/mol
Synonyms	Ethyl 6-bromo-5-methoxy-1H-indole-2-carboxylate; 6-Bromo-5-methoxyindole-2-carboxylic acid ethyl ester; 2-Carbethoxy-6-bromo-5-methoxyindole; 1H-Indole-2-carboxylic acid, 6-bromo-5-methoxy-, ethyl ester; Ethyl 6-bromo-5-methoxyindole-2-carboxylate; 128593-40-8; 6-Bromo-5-methoxy-1H-indole-2-carboxylic Acid Ethyl Ester
EINECS	Contact for details

Quality Control

Our Ethyl 6-Bromo-5-Methoxyindole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (IR, NMR), to ensure it meets the high standards required for research and development. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Keep away from heat and incompatible materials. This product is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥97.0% (Area %)
Assay	≥95.0% (by HPLC normalization)
Melting Point	Contact for details
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.